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Cold therapy reduces pain by desensitizing nerves and reducing swelling.

Inflammation occurs at specific sites within the body, for example an injury, or can be systemic. Cold therapy reduces localized inflammation from exercise and injuries by reducing edema. Systemic inflammation is usually identified through blood samples and identification of specific hormone markers. Cold therapy reduces systemic inflammation through changes in hormones due to stimulation of the Vagus nerve complex.

Cold therapy can help alleviate depression and anxiety. Research indicates that people with depressive symptoms typically have inflammatory markers and cold therapy significantly improves both the systemic inflammation and depression and anxiety symptoms. Cold therapy is a non-pharmaceutical supporting therapy.

Cold therapy activates hormonal responses in healthy people as well those suffering from chronic diseases such as depression, fibromyalgia, and rheumatoid arthritis. This reduces whole-body inflammation and has antioxidant effects.

Heart Rate Variability is an indicator of physical and psychological stress. Cold therapy reduces stress and improves exercise recovery times as shown by improved heart rate variability.

Cold therapy initiates vasoconstriction of blood vessels in the skin and extremities, which aids in reducing muscle pain, fatigue, and swelling. Cold therapy initiated vasoconstriction may be a preventative measure against dementia including Alzheimer’s Disease.